It’s best you don’t use it on anyone under the age of 12 unless instructed by their pediatrician. The safety of ketoconazole also hasn’t been well-studied in children. If you’re pregnant and have concerns about using an antifungal treatment, talk to your doctor before using even the OTC version of this antifungal shampoo. Ketoconazole’s effects on women who are pregnant or breastfeeding aren’t well-studied.
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One of the most common side effects is skin irritation, which can take the form of pimple-like bumps where it’s used.
Ketoconazole can have negative side effects that you should be aware of before using it. One small pilot study consisting of 15 people with alopecia, for example, found that ketoconazole may be able to improve hair regrowth. While ketoconazole is most frequently used for its antifungal properties to treat infections or conditions like seborrheic dermatitis, there is anecdotal evidence indicating that it may also help promote hair growth or reduce hair loss. Tinea versicolor is a skin infection that’s caused by an overgrowth of a type of yeast that naturally lives on your skin. Tinea capitis is a superficial, ringworm-like fungus infection that affects the scalp. Ketoconazole shampoo can also treat tinea capitis and tinea versicolor. Prescription ketoconazole may be needed for psoriasis flares. Yeast-like fungus often infects these skin plaques. Ketoconazole is a common treatment for psoriasis, another inflammatory skin disease that causes skin flaking, skin plaques, and redness. Ketoconazole can help treat dandruff by reducing the fungus and inflammation. Seborrheic dermatitis may be associated with an overgrowth of Malassezia, a yeast fungus that’s naturally present on your skin. Dry scalp causes some dandruff, while other dandruff is actually seborrheic dermatitis. If you no longer wish to have this DailyMed RSS service, simply delete the copied URL from your RSS Reader.Ketoconazole shampoo is commonly advertised as a dandruff treatment, with OTC brands like Nizoral available in supermarkets or online for purchase.
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To view updated drug label links, paste the RSS feed address (URL) shown below into a RSS reader, or use a browser which supports RSS feeds, such as Safari for Mac OS X. What will I get with the DailyMed RSS feed?ĭailyMed will deliver notification of updates and additions to Drug Label information currently shown on this site through its RSS feed.ĭailyMed will deliver this notification to your desktop, Web browser, or e-mail depending on the RSS Reader you select to use. To receive all DailyMed Updates for the last seven days KETOCONAZOLE (UNII: R9400W927I) (KETOCONAZOLE - UNII:R9400W927I)ģ0 g in 1 TUBE Type 0: Not a Combination ProductĬopy the URL below and paste it into your RSS Reader application. It is postulated that the therapeutic effect of ketoconazole in seborrheic dermatitis is due to the reduction of In vitro studies suggest that ketoconazole impairs the synthesis of ergosterol, which is a vital component of fungal cell membranes. Development of resistance to ketoconazole has not been reported.
Only those organisms listed in the INDICATIONS AND USAGE Section have been proven to be clinically affected. Malassezia furfur (Pityrosporum orbiculare). tropicalis and the organism responsible for tinea versicolor, Yeasts: Candida albicans, Malassezia ovale (Pityrosporum ovale) andĬ. Ketoconazole is a broad spectrum synthetic antifungal agent which inhibits the in vitro growth of the following common dermatophytes and yeasts by altering the permeability of the cell membrane: dermatophytes:
Two dermal irritancy studies, a human sensitization test, a phototoxicity study and a photoallergy study conducted in 38 male and 62 female volunteers showed no contact sensitization of the delayed hypersensitivity type, no irritation, no phototoxicity and no photoallergenic potential due to Ketoconazole Cream, 2%. When Ketoconazole Cream, 2% was applied dermally to intact or abraded skin of Beagle dogs for 28 consecutive days at a dose of 80 mg, there were no detectable plasma levels using an assay method having a lower detection limit of 2 ng/ml.Īfter a single topical application to the chest, back and arms of normal volunteers, systemic absorption of ketoconazole was not detected at the 5 ng/ml level in blood over a 72-hour period.
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